How Gene Universal Leads the Way in Protein Engineering with TEV Protease His Tag Technology

In the ever-evolving landscape of life science research, precision, efficiency, and scalability are crucial. Among the many powerful tools enabling breakthroughs in protein engineering, TEV protease with His tag stands out for its unmatched specificity and versatility. At the forefront of this innovation is Gene Universal, a global technology and service provider committed to accelerating scientific discovery and reducing biologics production costs.

A Trusted Innovator in Life Sciences

Gene Universal has emerged as a pioneer in life science R&D, providing researchers worldwide with cutting-edge technologies and high-performance solutions. With a mission rooted in advancing human health and environmental sustainability, the company consistently delivers tools that empower scientists to push the boundaries of protein science.

By focusing on precision, cost-efficiency, and sustainability, Gene Universal has built a reputation as a reliable partner for labs, research institutions, and biotech companies alike.

TEV Protease His Tag: The Engine Behind Efficient Protein Cleavage

TEV Protease—short for Tobacco Etch Virus protease—is a site-specific recombinant protease derived from the TEV Nla protein. It is widely used for the removal of affinity tags from fusion proteins, particularly when purity and biological activity are paramount.

What sets Gene Universal’s TEV protease with His tag apart is its optimized expression and purification through E. coli recombinant technology, resulting in a highly active and reliable enzyme.

Key Advantages of Gene Universal’s TEV Protease:

  High Site Specificity: Recognizes the 7-amino-acid cleavage sequence ENLYFQ↓G/S,enabling precise tag removal without affecting target proteins.

  Flexible Reaction Conditions:Functions effectively across a pH range of 5.5 to 8.5 and temperatures from 4°C to 30°C, offering flexibility for various protein environments.

  His-Tagged Purification: The inclusion of a His tagallows easy post-reaction removal of the protease via affinity chromatography, ensuring higher purity in the final protein product.

  Scalable and Cost-Effective: Suitable for both small-scale lab experiments and industrial-scale bioprocesses,making it a valuable asset across diverse applications.

Driving the Future of Protein Engineering

The integration of TEV protease with His tag into protein purification workflows reflects Gene Universal’s broader commitment to innovation. With each batch manufactured under strict quality controls, researchers benefit from consistent performance, batch-to-batch reproducibility, and maximum cleavage efficiency.

Whether it’s removing tags to improve protein solubility or preserving the functional activity of therapeutic proteins, Gene Universal’s TEV protease solution helps researchers meet critical project goals faster and more affordably.

Why Choose Gene Universal?

  Global Reputation for reliability and R&D support

  Advanced production platforms and purification technologies

  Customization options for specific research or biomanufacturing needs

  Fast delivery,high purity, and full documentation for regulatory compliance

Conclusion

Protein engineering demands tools that offer precision, flexibility, and dependability—and that’s exactly what Gene Universal’s TEV Protease His Tag technology delivers. As a trailblazer in the life sciences industry, Gene Universal continues to set the standard for enzyme innovation, empowering scientists to transform research into real-world impact.

Discover how TEV protease from Gene Universal can elevate your protein expression workflows today.