AI Shines with the Nobel Prize! High-throughput Antibody Expression Platform Fuels AI-Driven Next-Generation Antibody Discovery

The 2024 Nobel Prize in Chemistry was awarded half to David Baker for his contributions to computational protein design, and the other half jointly to Demis Hassabis and John M. Jumper for their contributions to protein structure prediction. Demis Hassabis and John M. Jumper successfully utilized artificial intelligence technology to predict the structures of nearly all known proteins, while David Baker mastered the building blocks of life and created entirely new proteins.

Trimer-Based Gene Library Service – Enhancing Library Precision and Accuracy

Gene libraries are essential tools in molecular biology and genomics, widely used in gene function research, gene cloning, and drug screening. Conventional gene library construction methods, such as degenerate saturation mutagenesis using NNK or NNS degenerate primers, include 32 (4×4×2) codon combinations corresponding to 20 amino

How Much Do You Know About the Prokaryotic Expression System?

E. coli protein expression system is the most commonly used expression system for recombinant proteins. Prokaryotic expression vectors generally consist of the replicon, promoters, selection markers, multiple cloning sites (MCS) and fusion tags / restriction sites.