Synthetic sgRNA

OVERVIEW

Synthetic single-guide RNA (sgRNA) is produced through advanced chemical synthesis. This method provides a straightforward and cost-effective way to enhance CRISPR editing, offering benefits such as higher editing efficiency, lower cytotoxicity, and improved lot-to-lot stability compared to IVT sgRNA.Our synthetic sgRNAs have demonstrated effectiveness in targeted gene editing for both knockout and HDR-mediated knock-in experiments. When combined with Cas9 protein to form a ribonucleoprotein (RNP) complex, these sgRNAs offer additional advantages over traditional plasmid or virus-based delivery systems, including reduced immunogenicity and minimized off-target effects.

SERVICE DETAILS

Service	Length	Quantity	Price	Specification
• SwiftEdit sgRNA	97-103 nt	3 nmol	$79	Research Purpose, Cost-effective
		5 nmol	$139
		10 nmol	$289
		50 nmol	$819
		100 nmol	$1,279
		>100 nmol	Inquiry
• PrecisionEdit sgRNA		3 nmol	$109	Research Purpose, Purity≥ 90%
		5 nmol	$199
		10 nmol	$449
		50 nmol	$1,279
		100 nmol	$1,879
		>100 nmol	Inquiry