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OVERVIEW
The Lentivirus vector, derived from HIV-1 and incorporating the coat protein of herpes virus VSVG, serves as a potent gene therapy vector. Operating as a retrovirus, its virulence gene is replaced by an exogenous target gene. This vector efficiently integrates the exogenous gene into the host chromosome, enabling persistent expression. With versatile infection capabilities, it effectively targets neurons, hepatocytes, cardiomyocytes, tumor cells, endothelial cells, stem cells, and other cell types, ensuring robust gene transduction effects.
ADVANTAGES
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Wide Range of Infection
The Lentivirus vector infects both dividing and non-dividing cells& efficiently,including primary cells
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Stable Expression
After infecting the host cell, Lentivirus integrates the exogenous gene into the host cell's genome, enabling continuous and stable expression through cell division
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High Safety
Lentivirus is a recombinant replication-defective strain, ensuring operational safety as it cannot autonomously replicate
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Integrated exogenous gene fragments are resistant to gene silencing
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Capable to carry relatively large exogenous fragments, up to 4.8 kb
SERVICE DETAILS
Explore our Lentivirus packaging options, featuring 2nd- and 3rd-generation systems for coding and non-coding gene manipulation. Discover a diverse range of Lentivirus vectors for your selection
| Scale | Package | Titer | Turnaround | Price |
|---|---|---|---|---|
| Medium | Customized Over-expression Lentivirus ( gene ≤ 3kb ) | ≥ 108 TU/ml | 25 BD | $499 |
| Customized RNAi Lentivirus ( single target ) | ≥ 108 TU/ml | 25 BD | $309 | |
| Customized RNAi Lentivirus ( Design 3 targets, 1 target with guaranteed effect ) | ≥ 108 TU/ml | 25 BD | $769 | |
| Customized sgRNA Lentivirus ( single target ) | ≥ 108 TU/ml | 25 BD | $389 | |
| Customized sgRNA Lentivirus( three targets ) | ≥ 108 TU/ml | 25 BD | $929 | |
| Large | Customized Over-expression Lentivirus ( gene ≤ 3kb ) | ≥ 109 TU/ml | 30 BD | $1,759 |
| Customized RNAi Lentivirus | ≥ 109 TU/ml | 30 BD | $1,659 | |
| Customized sgRNA Lentivirus ( single target ) | ≥ 109 TU/ml | 30 BD | $1,679 |
* Listed price includes RNA synthesis. For Customized Over-expression Lentivirus, a $0.12/bp gene synthesis fee applies.
* Turnaround time includes plasmid construction and preparation.
Download Lentivirus VectorsDELIVERABLES
| Product | Lentivirus packaging services |
|---|---|
| Deliverables |
Custom Lentivirus, delivered to specification: Medium Scale: ≥ 108 TU/ml, 5 x 200 μl Large Scale: ≥ 109 TU/ml, 5 x 200 μl |
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Free: Control virus Medium Scale: > 108 TU/ml, 5 x 200 μl Large Scale: > 109 TU/ml, 5 x 200 μl |
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Polybrene, 10 mg/ml, 1 x 200 μl (Free) |
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| Transport/storage |
Dry ice/-80 ° C, avoid repeated freezing and thawing |
HELPER VIRUS
| Helper virus | Vector Name | Vector ID | Customized virus service |
|---|---|---|---|
| Cas9 Lentivirus | VP025-SFFV-Cas9-2A-Puro | VP025 |
Mammalian gRNA Lentivirus (without Cas9) |
Transport/storage：
Lentivirus will be shipped in buffer on dry ice
Upon receipt, store Lentivirus at -80℃.
Validity period: 1 year.
Avoid repeated freezing and thawing to maintain Lentivirus titer.
CASE STUDY
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Fluorescence microscopy imaging performed after cell infection
EVI5 lentiviral infection of 293T cells (bright field)
EVI5 lentiviral infection of 293T cells (green fluorescence)
Lentivirus Packaging FAQs
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